Dated: January 1, 2020 – John Hopkins University 1. The purpose of this study was to measure the effects of CBD increase movement and promote calmness in horses. CBD was studied in horses after the administration of two oral doses (50 mg each) each day over a two-week timeframe. Forty-one horses were studied across the …
Dated: March 26, 2021 The purpose of this study was to determine the safety and tolerability of escalating doses of orally delivered cannabis oils predominant in cannabidiol (CBD), tetrahydrocannabinol (THC), or both CBD and THC in healthy cats. In this placebo-controlled, blinded study, 20 healthy adult cats were randomized to one of five treatment groups …
Safety and tolerability of escalating cannabinoid doses in healthy cats Read More »
Dated: November 28, 2020 The objectives of this study was to explore the anti-proliferative and cell death response associated with in vitro treatment of canine cancer cell lines with CBD alone and combination with common chemotherapeutics, as well as investigation into major proliferative pathways (eg, p38, JNK, AKT and mTOR) potentially involved in the response …
Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy – 2019 Stephanie McGrath, Lisa R Bartner, Sangeeta Rao, Rebecca A Packer, Daniel L Gustafson The Objective was to assess the effect of oral cannabidiol (CBD) administration …
Single-Dose Pharmacokinetics and Preliminary Safety Assessment with Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats – 2019 Kelly A. Deabold, Wayne S. Schwark, Lisa Wolf, and Joseph J. Wakshlag The purpose of this study was to determine the pharmacokinetics and preliminary safety of an oral canine whole-plant CBD-infused soft chew and oral feline …
Clinical Trials – Safety in Cats and Dogs – 2019 Read More »
Dana Vaughn, Justyna Kulpa, and Lina Paulionis Objective: To determine the safety and tolerability of escalating doses of three cannabis oil formulations, containing predominantly CBD, THC, or CBD and THC vs. placebo in dogs. Design: Randomized, placebo-controlled, blinded, parallel study. Animals: Twenty healthy Beagle dogs (10 males, 10 females). Methods: Dogs were randomly assigned to …
Pharmacokinetics, Safety and Clinical Efficacy of Cannabidiol Treatment of Osteoarthritic Dogs. July 2018 1-The objectives of the study were to determine basic oral pharmacokinetics and assess safety and analgesic of a cannabidiol (CBD) based oil in dogs with osteoarthritis (OA). 2- Single-dose administrations were performed using two different doses of CBD enriched (2 mg and …
Clinical Trial Pharmacokinetics, Safety and Clinical Efficacy of CBD Treatment Read More »
A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain – 2020 Chris D. Verricoa, Shonda Wessonc , Vanaja Kondurid , Colby J. Hofferekd , Jonathan Vazquez-Perezd , Emek Blaire, Kenneth Dunner, Pedram Salimpourg , William K. Deckerd, Matthew M. Halpertd Method: Cannabidiol, provided by MedterraCBD (Irvine, CA), was isolated …
Journal of the American Holistic Veterinary Medical Association (JAHVMA). Article first appeared in Volume 52, Fall Issue, 2018. 1) The purpose of this study was to determine the tolerability of cannabidiol (CBD) by healthy dogs. The scientists hypothesized that CBD would be tolerated in a healthy population of dogs. A group of 30 healthy Beagle …
Randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis. April 2020 1-The cannabidiol used was provided by MedterraCBD (Irvine, CA), free from THC and the Hemp used was farmed under the strict guidelines of the Department of Agriculture Industrial Hemp pilot program. The CBD used was a 99.99% pure isolate combined …
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